Content

The content of medical knowledge in this section of the site of the Lactology Foundation is intended for the practical needs of doctors, pharmacists and students in these specialties. It is more than reasonable to consult other authoritative medical sources before using our medical knowledge.

Retroperitoneal Pain

Pain that originates from the retroperitoneal region generally radiates to the back, the lumbar region on both sides of the spinal column, and, more rarely, to the flanks and ventrally.
Spinal diseases must be excluded first.

Classification. Retroperitoneal pain can be classified as
follows:
➤ acute or chronic
➤ caused by benign or malignant diseases
➤ caused by renal or non-renal diseases.
The transitions are smooth, particularly because ureteral blockage is a very common cause of retroperitoneal pain, and can generally be diagnosed by sonography, intravenous urography, CT or MRI.
Causes. Important causes are:
➤ nephrolithiasis or urolithiasis with typical ureteral colic
➤ papillary necrosis
➤ hydronephrosis of various etiologies.

Retroperitoneal Fibrosis
The clinical picture of retroperitoneal fibrosis can be associated with severe lower back pain.
It can be classified into:
➤ the idiopathic form: Ormond disease
➤ symptomatic retroperitoneal fibrosis: Ormond-like alterations resulting from:
− inflammatory processes (e.g., pancreatitis, distal ileitis, diverticulitis, tuberculous spondylitis, appendicitis, inflammatory aortic aneurysm)
− tumors (malignant lymphomas, lymph node metastases [e.g., testicular tumors, consequences of radiation therapy])
− certain drugs (e. g., methysergide).
The fibrosis may result in unilateral or bilateral ureteral obstruction with the corresponding consequences.
Differential Diagnosis
If there is no ureteral obstruction, the following causes of retroperitoneal pain must be considered:
➤ acute appendicitis of retroperitoneal appendix
➤ psoas abscess
➤ renal infarction
➤ retroperitoneal hematoma (e.g., in patients receiving
anticoagulants)
➤ Wilms tumors (in children)
➤ aortic dissection
➤ vertebrogenic causes (disk disease, spondylitis).

Please see also our Toxilact data base which is in the following language versions:

نسخة اللغة العربية Toxilact

Toxilact中文版

Toxilact česká jazyková verze

Toxilact dansk sprogversion

Toxilact Deutsche Sprachversion

Toxilact Nederlandstalige versie

Toxilakt έκδοση στην ελληνική γλώσσα

Toxilact English language version

Version française de Toxilact

Toxilact magyar nyelvű változat

Toxilact versione in lingua italiana

トキシラクト 日本語版

גרסת השפה הישראלית רעילה

Toxilact norsk språkversjon

Toxilact polska wersja językowa

Toxilact versão em português

Токсилак русскоязычная версия

Toxilac versión en idioma español

Toxilact svensk språkversion

Toxilact Türkçe dil versiyonu

If our cause of developing a less toxic world and healthier babies in it appeals to you, you can support us with a donation!

Detailed medical information on more common causes of acute abdomen

Intestinal Pain

Acute Appendicitis

Peritoneal Pain

Pain from Vascular Causes

Retroperitoneal Pain

Abdominal Pain from Intoxication


Toxicological risk during lactation

Toxicological lactation category I - the drug and/or its metabolites are either not eliminated through breast milk or are not toxic to the newborn and cannot lead to the development of absolutely any toxic reactions and adverse consequences for his health in the near and long term. Breast-feeding does not need to be discontinued while taking a given drug that falls into this toxicological lactation category.

Toxicological lactation category II - the drug and its metabolites are also eliminated through breast milk, but the plasma:milk ratio is very low and/or the excreted amounts cannot generate toxic reactions in the newborn due to various reasons, including degradation of the drug in the acid pool of the stomach of the newborn. Breastfeeding does not need to be discontinued while taking this medicine.

Toxicological lactation category III - the drug and/or its metabolites generate in breast milk equal to plasma concentrations or higher, and therefore the possible development of toxic reactions in the newborn can be expected. Breastfeeding should be discontinued for the period corresponding to the complete elimination of the drug or its metabolites from the mother's plasma.

Toxicological lactation category IV - the drug and/or its metabolites generate a plasma:milk ratio of 1:1 or higher and/or have a highly toxic profile for both the mother and the newborn, therefore their administration is incompatible with breastfeeding and it should to stop completely, and not just for the period of taking the drug, or to look for a less toxic therapeutic alternative.