TOXYLACT
The first professional lAtological database in the word
TOXYLACT – Toxicopharmacological Database for Safe Breastfeeding
Welcome to TOXYLACTTOXYLACT is the first specialized toxicopharmacological database dedicated exclusively to the safety of medications, chemicals, and environmental exposures during human lactation. Developed by Foundation Lactology, this powerful digital tool is designed to provide healthcare professionals and breastfeeding mothers with rapid, evidence-based answers to one of the most pressing questions in daily clinical practice:
"Is this medication safe for my breastfeeding baby?"
Why Is a Dedicated Toxico-Lactological Database Necessary?
For decades, healthcare providers have relied on fragmented, outdated, or overly cautious information when prescribing medications to breastfeeding mothers. Standard drug labels often lack specific lactation data, general toxicology databases do not account for the unique physiology of the lactating breast and the nursing infant, and internet forums spread fear-based misinformation.
The result? Unnecessary interruption of breastfeeding, discontinuation of essential maternal treatment, and, in some cases, preventable infant exposure to unsafe substances.
TOXYLACT fills this critical gap by offering:
Integrated pharmacokinetic modeling – how drugs transfer from maternal plasma to breast milk.
Infant-specific toxicological profiles – accounting for immature metabolic pathways (e.g., cytochrome P450, glucuronidation).
Real-time risk stratification – based on Relative Infant Dose (RID), milk-to-plasma ratio, and half-life in breast milk.
Updates with emerging evidence – including new drugs, biologics, and environmental contaminants.
Benefits for Different Users
For Healthcare Professionals (Physicians, Pharmacists, Clinical Toxicologists)
Confident clinical decisions – replace guesswork with robust, referenced data.
Time efficiency – instant access to curated, peer-reviewed summaries.
Defensible prescribing – support treatment plans with documented risk-benefit analysis.
Reduced liability – rely on a professional-grade database rather than general sources.
For Breastfeeding Mothers
Peace of mind – know whether your medication is truly safe for your baby.
Avoid unnecessary weaning – continue breastfeeding while treating your own health condition.
Personalized information – search by drug name, category, or clinical scenario.
Empowerment – make informed decisions together with your healthcare provider.
For Their Children (Infants and Toddlers)
Protection from harm – avoid known toxic exposures through breast milk.
Preserved benefits of breastfeeding – continued access to optimal nutrition, immune factors, and maternal bonding.
Long-term safety – our data considers not only acute toxicity but also potential neurodevelopmental and endocrine effects.
The True Cost of Creating TOXYLACT
Building a reliable, comprehensive, and user-friendly toxico-lactological database is neither quick nor inexpensive. The challenges we face include:
Highly specialized scientific team – clinical pharmacologists, lactation experts, toxicologists, and data scientists.
Systematic literature review – thousands of original research papers, case reports, and regulatory documents.
Pharmacokinetic modeling – developing and validating algorithms for drug transfer prediction.
Multilingual and global relevance – covering drugs marketed in different countries.
Continuous updating – adding new medications and revising entries as new evidence emerges.
Software development and security – a robust, fast, and secure web-based platform.
TOXYLACT is a long-term, expensive endeavor. We have invested significant resources to launch the initial version, but we need substantial additional funding to:
Complete the full database (thousands of active substances).
Reduce the time to final release (from years to months).
Ensure free or low-cost access for healthcare professionals in low-resource settings.
We Need Your Support – This Is an Unequal Fight
We are a non-profit foundation competing against well-funded commercial databases that often ignore lactation safety or provide overly simplistic, fear-based warnings. We fight for objective, baby-protective, evidence-based toxico-lactological information – free from commercial bias and driven only by science and the best interest of mothers and children.
But we cannot win this fight alone!
We kindly ask you to visit our Donations Page (linked below). Read about our funding needs, our transparent budget, and the specific milestones your contribution will help achieve. Every donation – large or small – brings us closer to a world where no mother has to choose between her own health and breastfeeding her baby.
Together, we can build TOXYLACT – for safer breastfeeding, for informed healthcare, for the health of future generations.
